What
do doctors call this condition?
Sarcoma of the bone, bone cancer,
primary malignant bone tumor
What
is this condition?
Most bone tumors are caused by the
spread of cancer from another part of the body (secondary tumors).
Tumors that originate in the bones
themselves (primary tumors) are rare, accounting for less than 1 % of all
malignant tumors. Primary tumors are more common in young males, but may affect
individuals between ages 35 and 60 as well.
What
causes it?
The causes of a primary malignant
bone tumor are unknown. Some researchers suspect that the tumor arises in areas
of rapid body growth because children and young adults with such tumors seem to
be much taller than average.
What
are its symptoms?
Bone pain is the most common symptom
of a primary malignant bone tumor. Often more intense at night, the pain isn’t
usually associated with movement. It’s dull and usually localized, although it
may be referred from the hip or spine and result in weakness or a limp.
Another common sign is a mass or
tumor. The tumor site may be tender and swollen; the tumor itself often can be
felt. Fractures are common. In late stages, the person may have a fever,
impaired mobility, and physical wasting and malnutrition.
How
is it diagnosed?
A biopsy is essential for confirming
a primary malignant bone tumor. Bone X-rays, radioisotope bone scans, and CAT
scans show tumor size.
How
is it treated?
This may be combined with
preoperative chemotherapy using drugs such as doxorubicin, vincristine,
cyclophosphamide, cisplatin, and dacarbazine administered through the arteries
to the long bones of the legs. In some instances, radical surgery such as
amputation is necessary.
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